Called benzodiazepines, these uber drugs ‘ve long been prescribed to treat a variety of mood disorders. However, a new Canadian study finds that when taken in early pregnancy, they rez th'risk for a miscarriage inna 1st trimester by 11%.
dration use in pregnancy is a tricky business, experts say.
“In drations in pregnancy, physicians ‘ve to decide, are the risks higher than the benefits, cause there isn’t any risk zero,” said lead researcher Anick Berard. She’s a professor atta Centre Hospitalier Universitaire Sainte-Justine in Montreal.
In this case, drs must balance the severity odda woman’s mood problem against possible harm to the developing fetus, she said.
For the study, Berard and her colleagues collected data on bout 442,000 pregnant Canadians from 1998 through 2015.
The study found that 6% of pregnancies ended in a miscarriage. Among those who miscarried, slitely + than 1% were taking a benzodiazepine for the 1st time in early pregnancy.
Berard said that it didn’t matter which benzodiazepine a woman took, as all were linked with an increased risk for miscarriage. Besides Valium (diazepam) and Xanax (alprazolam), this class of drugs includes Ativan (lorazepam) and Klonopin (clonazepam).
Berard cautioned, however, that this study can’t prove that tranquilizers cause miscarriages, 1-ly that an association exists.
And the researchers were unable to account for smoking and alcohol use, which may also increase risk for miscarriage.
Exactly how these drugs are linked witha failed pregnancy isn’t known. But animal studies ‘ve shown that benzodiazepines affect fetal development and rez miscarriage odds, Berard said.
And she sufferationed that although benzodiazepines may negly affect pregnancy, so can anxiety and insomnia.
Women ‘d not stop taking their benzodiazepines, but ‘d ‘ve a discussion with their dr bout the risks and benefits of these drugs, Berard said.
“Anxiety and insomnia are serious mental health issues, and they are relatively common in pregnancy,” said Catherine Monk, a professor of med ψ-chology in obstetrics and gynecology at Columbia University.
Original content at: www.webmd.com…